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Sickle cell disease can cause unique problems in women. In addition to the major complications of sickle cell disease, if you are a woman with sickle cell disease, you may also have:
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Delayed puberty 
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More pain crises during the years you have your period and before and during your period. 
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Increased sickle cell disease complications during pregnancy Problems during pregnancy for you and for your baby. 
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Problems getting pregnant due to sickle cell disease treatments. 
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Sickle cell disease | Office on Women's Health (womenshealth.gov) 
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